Hyatt Key West Resort & Marina, in Old Town

Among mainstream Key West resorts, it's hard to beat the Hyatt Key West Resort & Marina in terms of location (it's at 601 Front St., right in Old Town and close to Lower Duval Street, tel 305-809-1234). This sprawling, attractive low-rise property sits right on the Gulf side of the island, affording water views from many rooms. There are just 118 rooms, outfitted with flat-screen TVs and dapper furnishings, and the pool area is one of the prettiest in town. A surprising number of gay and lesbian travelers to Key West opt for a mainstream property over a gay-specific one - it's a better fit if you're seeking a little more anonymity, you prefer the more substantial facilities of a resort, or you're just a fan of the Hyatt brand, an extremely gay-friendly company according to its rating in the Human Right Campaign Buyers Guide.